"His mind slid away into the labyrinthine world of doublethink. To know and not to know, to be conscious of complete truthfulness while telling carefully constructed lies, to hold simultaneously two opinions which cancelled out, knowing them to be contradictory and believing in both of them, to use logic against logic, to repudiate morality while laying claim to it, to believe that democracy was impossible and that the Party was the guardian of democracy, to forget, whatever it was necessary to forget, then to draw it back into memory again at the moment when it was needed, and then promptly to forget it again, and above all, to apply the same process to the process itself — that was the ultimate subtlety; consciously to induce unconsciousness, and then, once again, to become unconscious of the act of hypnosis you had just performed. Even to understand the word 'doublethink' involved the use of doublethink."
George Orwell, from "1984"
Mar 19, 2013 - The age-adjusted death rate from Alzheimer's disease increased by 39 percent from 2000 through 2010 in the United States.
February 22, 2016 - Study: Scientists Baffled as Risk of Dementia Declining
February 22, 2003 - Cell Phones 'May Trigger Alzheimer's Disease'
January 6, 2010 - Can Cell Phones Help Fight Alzheimer's? - WebMD
If blood-brain barrier Leakage is the driver of Alzheimer's Disease:
2005 - "We hypothesize that BBB dysfunction may contribute to the development of overlapping and disabling cerebrovascular conditions that include microvascular hemorrhage and dementia."
May 31, 2016 - "Leaky blood-brain barrier linked to Alzheimer's disease."
And microwave radiation causes the blood-brain barrier to leak:
Dr. Leif Salford exposed over 1600 experimental animals to low level microwave radiation. Their results were consistent and worrisome: microwave radiation. . ..caused the blood-brain barrier . . .to leak.” (It was repeated in 2003 on 32 additional animals; they waited this time 8 weeks before “sacrificing them”–and found “up to two percent of the neurons in all areas of the brain were shrunken and degenerated. ”Dr. Salford, says Firstenberg, called the “potential implications ‘terrifying."
Then Smart Phones Cause Alzheimers.
The words "mystery", "baffled" and "puzzled" are memes, used, among numerous similar variants, whenever anyone in the wholly-controlled-and-coopted Political, Academic, Scientific and Media establishments wants to lie about, well, basically anything:
January 30, 2000 - Alzheimer's Unlocking The Mystery - Newsweek
July 29, 2010 - Inside the Brain: Unraveling the Mystery of Alzheimer's Disease
February 11, 2013 - The Only Predictable Aspect of Alzheimer's Is Its Baffling Unpredictability!
August 28, 2014 - NIH grant may help unlock Alzheimer's mystery - Florida State ...
February 22, 2016 - Study: Scientists Baffled as Risk of Dementia Declining
September 26, 2016 - 6 Big Mysteries of Alzheimer's Disease - Live Science
November 28, 2016 - Plaques, tangles and the mystery of Alzheimer's disease
April 21, 2017 - Are oligomers the missing piece of the amyloid puzzle to open a path for Alzheimer’s drugs?
May 5, 2017 - Medical Researchers Still Puzzled On Alzheimer's « CBS Philly
May 5, 2017 - Alzheimer's disease continues to baffle neuroscientists around the world.
The rates of Alzheimer's disease and demential were flat through the 1970's, and actually declined from 1982 to 1999. But then, in 2000, something changed. the age-adjusted death rate for Alzheimer's disease increased 39% from 2000 to 2010.
Last year, Dementia and Alzheimer’s disease overtook heart disease as the leading cause of death in the United States. In the U.K., the latest figures show that dementia is now the leading cause of death there, also. Last year, more than 61,000 people died from dementia, or 11.6 percent of all recorded deaths, there.
The official explanation? "Rising awareness" - that doctors have simply gotten more skilled at diagnosing dementia. Do you think that the death rate from Alzheimer's increased 40% in ten years because doctors had just missed it before?
Two-thirds of those afflicted with Alzheimer's disease are women. Last year in the U.K., 41,283 women were found to have died from dementia-related illnesses, compared to 20,403 men last year. Twice as many Alzheimer's deaths among women, versus men.
The official explanation? "Because women live longer". Women do live longer than men, but not a third longer, and certainly not twice as long.
The blood brain barrier separates the blood in the circulatory system from the fluid that surrounds the brain cells. It filters out possible neurotoxins, including bacteria, contained in the blood, and also allows nutrients that are essential to normal neurological function to pass.
That fact that leakage of the blood-brain barrier is the driver of Alzheimer's Disease has been known for over a decade, now. As has the fact that irradiation is one of the drivers of blood-brain barrier leakage. Microwave radiation causes the blood-brain barrier to leak, and the weakest exposure levels cause the greatest amount of leakage.
Even though the leaking blood-brain barrier has been documented as the driver of Alzheimer's disease since 2005, ruses including Amyloid beta oligomers, a gene encoding protein known as PICALM, and Herpes and Lyme disease microbes have all since been put forth in an attempt to draw attention away from that fact.
To solve the baffling mystery of Alzheimer's disease, we must answer: what did women in particular start doing around the year 2000 that involves ongoing, low-level doses of microwave radiation?
In 1999, NTT DoCoMo started i-mode Internet service.
In 2001, NTT DoCoMo premiered the world's first Third Generation mobile phone service (3G), using W-CDMA technology called FOMA.
In 2002, KDDI started 3G service in Okinawa, using CDMA2000 technology. In the same year, J-Phone started 3G service using W-CDMA technology.
February 22, 2003 - Cell Phones 'May Trigger Alzheimer's Disease'
BLOOD-BRAIN BARRIER LEAKAGE IS THE DRIVER OF ALZHEIMER'S, AND THAT FACT HAS BEEN KNOWN FOR OVER A DECADE. AS HAS THE FACT THAT IRRADIATION IS ONE OF THE DRIVERS OF BLOOD BRAIN BARRIER LEAKAGE:
2005 - Blood-Brain Barrier and Alzheimer's
The blood-brain barrier (BBB) was discovered when dyes, injected into living animals, stained all tissues except for most of the brain and spinal cord, leading to the postulated BBB. The BBB is a physiologic matrix of tissue that is selectively permeable and protective of the central nervous system (CNS). The BBB is located within the endothelium of cerebral capillaries and the choroids plexus epithelium. The BBB preserves concentrations within the CNS through reciprocal homeostatic processes. The rate with which substances penetrate through to the brain tissue is inversely related to their molecular size and directly related to their lipid solubility. The factors that are responsible for transfer across the capillary partition include vesicular transport, diffusion, and filtration. Diffusion is quantitatively more important in terms of exchange of nutrients and waste materials. Filtration depends upon a balance of forces between hydrostatic and osmotic pressure gradients.1–7
BBB integrity can be compromised by hypertension, cerebrovascular ischemia, histologic and metabolic changes within barrier tissue cells, vascular disease, systemic metabolic disease, trauma, tumors, medications, noxious stimulation, infection, irradiation, transport and permeability alterations, and aging. Common central disease states involving BBB integrity include Binswanger's Disease, periventicular hyperintensities, ischemic cerebrovascular events, hypoxia-ischemia, septic encephalopathy, reactionary inflammatory mechanisms, HIV-induced dementia, multiple sclerosis, and Alzheimer's disease (AD).8–1
Vascular dystrophy has been shown to be involved in the deposition of the amyloid beta-protein in the brains of AD. Although the mechanism remains undiscovered, it has, however, been shown that more numerous deposits of A beta 40 and A beta 42 can be found in the brains of Alzheimer's patients than in non-demented controls. Together with evidence of no difference in the level of A beta 40 and A beta 42 in peripheral sera between AD and controls, it is suggested that a dysfunction of the BBB could induce abnormal transport of A beta from sera, and accumulation, into the CNS, playing a critical role in the development of AD.11–16
The aging of the central nervous system and the development of incapacitating neurological diseases, such as AD, is associated with a wide spectrum of histological and pathophysiological changes eventually leading to a diminished cognitive status. Various forms of cerebrovascular insufficiency, such as reduced blood supply to the brain or disrupted microvascular integrity, may occupy an initiating or intermediate position in the sequence of events ending with cognitive malfunction. Although the diverse triggers and stages of neuro-degenerative processes are incompletely defined, the contribution of cerebrovascular deficiencies has become recognized as an important, if not a necessary, antecedent.
We hypothesize that BBB dysfunction may contribute to the development of overlapping and disabling cerebrovascular conditions that include microvascular hemorrhage and dementia. This hypothesis could explain the link between ischemic cerebral small-vessel disease and several apparently clinically distinct dementia syndromes. This hypothesis is supported by pathological, epidemiological, and experimental studies in lacunar stroke and examinations of the BBB with magnetic resonance imaging (MRI).17 We believe that the significance of BBB dysfunction as an early neurophysiologic cascading step leading to disabling brain diseases has been underappreciated.
ALZHEIMER'S RATES AND DEMENTIA RATES WERE FLAT THROUGH THE 70'S, AND DECLINED FROM 1982 TO 1999:
January, 2011 - Rorsman et al. found no increased incidence of dementia and AD between the period from 1947 through 1957 and the period from 1957 through 1972 in a Swedish population study [22]. Similarly, there were no detectable trends in the incidence of dementia or AD from 1975 to 1984 in Rochester, Minnesota [23]. By contrast, Manton et al. found a decline in prevalence of dementia in the United States using data from the National Long Term Care Study from 1982 to 1999.
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January 6, 2010 - Can Cell Phones Help Fight Alzheimer's? - WebMD
January 6, 2010 - Cell phones protect memory, at least in mice - Health - Mental health ...
TWO-THIRDS OF THOSE AFFLICTED WITH ALZHEIMER'S ARE WOMEN - THE RUSE FLOATED TO EXPLAIN IT IS 'BECAUSE WOMEN LIVE LONGER':
Short-term trends in the incidence of AD in the Chicago Health and Aging Project (CHAP): 1997 to 2008
Incidence trends were obtained using data from CHAP [36]. CHAP is a population-based study in Chicago with substantial numbers of both African-American and White participants. The study began in 1993, when all residents age 65 years or older in a defined geographic area were invited to participate. Over time, additional people are invited to participate as they turn 65 years old. In this way, the number of living subjects remains fairly constant (between 6,000 and 7,000) and the full age distribution of the population is maintained. Data are collected in 3-year cycles. Any combination of 2 or more successive cycles is methodologically similar to a standard prospective cohort study (Fig. 4). Individuals are determined to be disease-free at the first of these cycles and a stratified random sample is evaluated for incidence of disease at the second of these cycles, 3 years later [37]. There have been a total of 4 cohort intervals. Evaluations for incident disease have been done approximately continuously since the beginning of the second cycle in 1997, for a total of 11 years. The total number of people who have contributed data to the project increased over time and is presently a little over 10,000.
These analyses used data from subjects receiving clinical evaluation in the second (first incident) data collection cycle through the fifth cycle from 1997 to 2008. A total of 1,695 subjects were evaluated over this period and 360 developed incident AD. The mean age of the sample was 80.0 years (SD, 5.8). The mean education level was 12.9 years (SD, 3.5) which is similar to the community population and to the US average. Most subjects were women (61.6%) because women have a longer average survival. African-Americans represented 52.5% of the sample.
BLOOD-BRAIN BARRIER LEAKAGE CAUSES ALZHEIMER'S, MICROWAVE RADIATION CAUSES THE BLOOD-BRAIN BARRIER TO LEAK. AND THE WEAKEST EXPOSURE LEVELS CAUSE THE GREATEST AMOUNT OF LEAKAGE:
June 18, 2012 - Electromagnetic Fields and Leakage of the Blood Brain Barrier: Dr. Leif Salford
The following video is a presentation of Dr. Leif Salford, neurosurgeon and researcher, discussing his animal studies on radio frequency radiation and its effects on the brain. “Dr. Salford,” writes Arthur Firstenberg in his paper Silent Wireless Spring, “exposed over 1600 experimental animals to low level microwave radiation. Their results were consistent and worrisome: microwave radiation. . ..caused the blood-brain barrier . . .to leak.” (It was repeated in 2003 on 32 additional animals; they waited this time 8 weeks before “sacrificing them”–and found “up to two percent of the neurons in all areas of the brain were shrunken and degenerated.”Dr. Salford, says Firstenberg, called the “potential implications ‘terrifying.'”
An argument is sometimes made (not necessarily accurately) to those who express concern about radiation from “smart” meters, Wi Fi, etc, that the radiation emitted from these devices is at such a low level that the public needn’t worry about it. However Dr. Salford’s studies showed opening up of the blood brain barrier from very low levels of radiation. In fact, Cindy Sage and Dr. David Carpenter write in a 2008 paper (Public Health Implications of Wireless Technologies) it was “the weakest exposure level [which] showed the greatest effect in opening up the BBB [blood brain barrier].”
BUT THEN, IN 2000, THEY INCREASED DRAMATICALLY, AND PARTICULARLY AMONG WOMEN:
June 28, 2013 - South Carolina has already seen a dramatic 17.9 percent increase in Alzheimer’s cases since 2000.
Both in South Carolina and around the country, reports are revealing that nearly two-thirds of those diagnosed with the disease are women.
THE ALZHEIMER'S DEATH RATE INCREASED 39% FROM 2000 TO 2010:
Mar 19, 2013 - The age-adjusted death rate from Alzheimer's disease increased by 39 percent from 2000 through 2010 in the United States.
'OLIGOMERS' ARE FLOATED AS THE DRIVER, TO DRAW ATTENTION AWAY FROM THE LEAKING BLOOD-BRAIN BARRIER:
November 29, 2013 - The oligomer cascade hypothesis, which states that oligomers are the initiating pathologic agents in Alzheimer’s disease, has all but supplanted the amyloid cascade hypothesis, which suggested that fibers were the key etiologic agents in Alzheimer’s disease.
THE RUSE IS ALREADY COLLAPSING, BUT 'FLAWED TRIAL DESIGN' IS ADVANCED TO TRY TO STOP THE COLLAPSE:
Is this paradigm shift warranted? Some would argue 'no’, based on failures of recent clinical trials. However, clinical trial design may be flawed by the selection of cohorts that are too advanced in their disease state [5]. It also is possible that metabolites of APP other than Aβ may be pathogenic [6, 7, 8]. Determining the temporal involvement of Aβ oligomers in human disease is crucial to elucidating the etiology of AD and the involvement of oligomers in it. As we shall discuss, this is very challenging.
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A RUSE:
A number of reports have pointed out that one of the most common methods for defining oligomer distributions, SDS-PAGE, may produce misleading results.
SO, WHAT DID WOMEN IN PARTICULAR START DOING IN EARNEST AROUND THE YEAR 2000?
PICALM IS FLOATED TO COVER THE LEAKY BLOOD-BRAIN BARRIER DRIVER:
July 22, 2015 - New Insights Into the Blood Brain Barrier
"In May, Zlokovic discovered the mechanism of action for an Alzheimer’s-implicated gene encoding protein known as PICALM. The PICALM-Alzheimer’s connection had been studied previously by Cure Alzheimer’s Research Consortium Chair Rudy Tanzi, Ph.D., and Zlokovic in a Cure Alzheimer’s Fund-supported study. Zlokovic, publishing his research in Nature Neuroscience, showed that PICALM is crucial for clearing Abeta across the BBB. PICALM variants associated with increased risk for Alzheimer’s lead to diminished expression of PICALM and faulty clearance of Abeta from the brain, leading to its accumulation both in the human brain and animal models of the disease. This suggests that, while Abeta is crucial in the subsequent cascade that leads to Alzheimer’s disease, the compromise of the BBB may happen earlier in the process, and may contribute directly to the destructive excess of Abeta in the brain.
'AGING' IS PUT FORTH AS THE DRIVER OF BLOOD-BRAIN BARRIER LEAKING:
August 20, 2015 - Blood-Brain Barrier Permeability in Aging and Alzheimer's Disease
With aging there are alterations in the BBB that are thought to contribute to the pathological processes in VCI and possibly also in AD (10). Studies of the effect of aging on the BBB, while not conclusive, suggest an increase in NVU permeability occurs over time.
THE LEAKING BLOOD-BRAIN BARRIER IS THE DRIVER:
May 31, 2016 - Leaky blood-brain barrier linked to Alzheimer's disease
Source:
Radiological Society of North America
Summary:
Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier of people with early Alzheimer's disease, according to a new study. The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the disease.
'MICROBES' ARE FLOATED TO DRAW ATTENTION AWAY FROM THE BLOOD-BRAIN BARRIER DRIVER:
May 21, 2016 - Controversial New Push to Tie Microbes to Alzheimer's Disease ...
A journal article says herpes virus and Lyme disease bacteria are behind the mind-robbing illness, but not all researchers are convinced
June 16, 2016 - The blood brain barrier is, as the name implies, a membrane that separates the blood in the circulatory system from the fluid that surrounds the brain cells. Its purpose is to filter out possible neurotoxins, including bacteria, contained in the blood. At the same time it allows to pass those nutrients that are essential to normal neurological function. Because of this selective screening system infections of the brain are rare. Conversely, when they do occur they can be extremely difficult to treat. The barrier also blocks many drugs from entering the brain from the bloodstream, including most antibiotics.
November 20th, 2016 - As Alzheimers and Dementia become number one killer it follows the increase in microwave radiation
Dementia and Alzheimer’s disease overtake heart disease as the leading cause of death in America
Sunday, November 20, 2016 by: J. D. Heyes
(NaturalNews) When you see a substantial shift in what is causing most humans to die, there are many questions scientists and researchers should be asking – about changes in the environment, changes in the food and changes in the way we treat illnesses (Big Pharma comes to mind).
So it’s likely researchers are now asking questions about why dementia and Alzheimer’s disease have taken over heart disease as the world’s leading cause of death. Hint: They may want to start with the fact that our wired world is having a really negative effect on our brains.
In any event, the BBC reports that in England and Wales, the latest figures show that dementia is now the leading cause of death. Last year, figures show that more than 61,000 people died from dementia, or 11.6 percent of all recorded deaths.
As per the Office for National Statistics, the change from heart disease to dementia as the primary killer is likely due to an aging population. But that doesn’t jibe, considering that heart disease – especially in the West – is tied to aging and several other lifestyle choices (like bad diets) that have not changed much.
‘Dementia is not an inevitable part of aging’
Still, the office said, people are living longer, and so deaths from other causes, including heart disease, have declined. And officials say that doctors have gotten more skilled at diagnosing dementia, so the condition is now given much more weight in death statistics.
The BBC noted that dementia deaths were seen in higher numbers in women than in men. In all, 41,283 women were found to have died from dementia-related illnesses, compared to 20,403 men last year.